If enemy members are more than the currently fighting macrophages can handle, a special substance is secreted. The name of this substance is "pyrogen" and it is a kind of alarm call.
After traveling a long way, "pyrogen" reaches the brain where it stimulates the fever-increasing centre of the brain. Once alerted, the brain sets off alarms in the body and the person develops a high fever. The patient with a high fever naturally feels the need to rest. Thus, the energy needed by the defence army is not spent elsewhere. The pyrogen produced by the macrophages is perfectly designed to trigger the fever-raising mechanism of the brain. Therefore, the macrophage, and the pyrogen, and the temperature-raising centre of the brain, and the brain have all to be created at the same time.
As is evident, there is a perfect plan at work. Every requirement is created flawlessly for this plan to succeed; the macrophages, the pyrogen substance and other similar substances, the fever-raising centre of the brain and the fever-raising mechanisms of the body…
In the absence of even one of these, the system would simply not work. Therefore, it can by no means be claimed that such a system could have originated step by step through evolution.
Who, then, has made this plan?
Who knows that the body's fever must rise, and that only that way the energy needed by the defence army will not be spent elsewhere?
Is it the macrophages?
Macrophages are merely tiny cells invisible to the naked eye. They do not have the capacity to think. They are living organisms that only obey an established superior order; they merely carry out their duties.
Is it the brain?
Definitely no. Nor does the brain possess any power to create or produce something. Just as in all other systems, in this system, too, it is in a position not to give orders, but to obey orders and submit to them.
Is it man?
Certainly not. This system protects man from certain death, although he is not even aware that such a perfect system is at work in his own body. Even if man were ever ordered to develop an army in his own body to fight the enemy and cause his fever to rise, and provide this army to work round the clock in his entire body, he would simply have no idea what to do.
Today, mankind is not even able to understand the details of the present order in the defence system, despite all the technology at its disposal - much less imitate it.
It is an obvious fac that man was created with all of his features in place. Willingly or unwillingly, he submits to his Creator and the systems He established. Just as everything else does…
…No, everything in the heavens and earth belongs to Him. Everything is obedient to Him. (Surat al-Baqara: 116)
Another incredible function of the macrophages is
supplying the lymphocytes, i.e., the B and T cells, which are the
real heroes of the defence system, with information about the enemy.
After phagocytosing the antigen, the antigen-presenting cells go to
the lymph nodes (lymphatic tissue) through the lymphatic channels.
Now, imagine a country having an exceedingly high population, around 100 trillion. The number of health care workers (lymphocytes) would then be 1 trillion. If we think that the world's current population is some 7 billion, the number of the people living in our imaginary country would be almost 14 million 285 thousand times the world's population. Would it be possible for all the members of a country with such a high population to have a check-up one by one, and moreover, several times in the same day?
You will surely say no, but this process is carried out in your body every day; lymphocytes roam throughout your body several times a day to do a health check.
Is it possible to attribute the extremely organized operation of such a great mass of living beings to coincidence?
Can coincidences account for each one of a trillion lymphocytes assuming such an arduous and demanding task?
Allah, the Lord of all Worlds, created each one of these one trillion lymphocytes and charged them with the responsibility of protecting man.
Lymphocytes play a very important role against major infectious diseases such as AIDS, cancer, rabies and tuberculosis, and serious ailments such as angina and rheumatism. Of course, this does not mean that lymphocytes do not have any role to play with other diseases. Even the common cold is nothing but a combat fought by the lymphocytes to keep those very dangerous common cold viruses away from the body.
The human body can defeat many of its enemies by using antibodies. This may lead you to wonder why lymphocytes intervene in the war directly when they already make a considerable contribution by producing antibodies. However, some microbes are so deadly that very strong chemical toxins are needed for their removal. Therefore, some lymphocytes use these chemical toxins and directly participate in the war.
How then would the defence system stop these enemies?
First, chemists and a laboratory would be needed to produce the toxin. The structure of the required material is too special to be formed by coincidence. Allah, Who knows that the human body will face such an enemy, or rather, Who created such an enemy for man to take warning, has also given the lymphocytes to synthesize this toxin.
So, is this chemical material satisfactory?
No, because this substance cannot freely circulate in the blood, as this would mean the death of our own cells as well.
How then will this toxin be used without causing any harm to our cells?
The answer to this question is hidden in the perfection of the creation of the lymphocytes. Toxins are placed in sacs located in the cell membrane of the lymphocytes. This helps the chemical weapon to be used easily. The lymphocyte injects this toxin only when it contacts the enemy cell, eventually killing it.
The lymphocytes come in two types: B cells and T cells.
B cells are the weapon factories of the body and they produce the proteins, called antibodies, which are meant to attack the enemy.
In their initial phase, the B cells rearrange the gene fragments that will form an antibody molecule. These genes are actively transcribed as soon as the rearrangement is complete. At this point, it is very important to note how a tiny cell can perform complex tasks such as arranging and transcription. What is arranged and transcribed is actually information. And information can be arranged and organized only by a being who possesses intelligence. Furthermore, the outcome after the arrangement is extremely important: this information will later be used in the manufacture of antibodies.
The transformation of B cells rapidly goes on. Upon an order coming from an unknown source, cells produce proteins called "alfa" and "beta", which surround the cell membrane. At a further level, a range of complicated processes are due to take place in the cell to enable it to produce some molecules that will enable it to bind to antigens. At the end of all these complicated operations, the cells turn into a factory that recognizes the enemy as soon as it makes contact with it, and is able produce millions of different weapons.
In that case, the other cells send a signal inside the B cell. This signal is actually an order for the cell to "commit suicide". Eventually, some enzymes in the nucleus of the cell are activated and they decompose the DNA of the cell. A perfectly working auto-control mechanism protects the body, and finally, only the B cells that produce antibodies that cause harm to the enemy can stay alive.
Only comprised of a compact nucleus and very little cytoplasm initially, the B cells undergo unbelievable changes when they meet an antigen. They divide repeatedly and build up thousands of assembly points in their cytoplasm for the manufacture of antibodies, as well as an extensive channeling system for the packaging and exporting the antibodies. One B cell can pump out more than 10 million antibody molecules an hour.
Here is a single cell that transforms itself into a factory competent enough to produce 10 million weapons an hour on meeting an enemy. If we remember that this cell can produce different weapons for each of its millions of enemies, we can better understand the scope of the miracle in question here.
Some B cells become "memory cells". These cells do not immediately participate in the body's defence, but keep molecular records of past invaders in order to accelerate a potential war in the future. Their memory is very strong. When the body meets the same enemy again, this time it is rapidly geared to the appropriate weaponry production. Thus, defence becomes faster and more efficient.
Here, we cannot help asking ourselves: "How can man, who considers himself the most advanced being, have a memory weaker than that of a tiny cell?"
Unable to explain even how the memory of a normal human being forms and works, evolutionists never attempt to explain the existence of such a memory as a matter of evolution.
If a lump of flesh the size of a hundredth of a millimeter had only one single piece of information, and used this information for the benefit of mankind in the most accurate way, even this would be a miracle in its own right. However, what we are referring to here goes far beyond that. The cell stores millions of pieces of information for the benefit of man and uses this information accurately in combinations beyond man's comprehension. Man is able to survive thanks to the wisdom these cells display.
Memory cells are cells specially created to protect man's health. Allah equipped them with strong memorizing ability by design. Otherwise, it would be impossible for the cell to develop a strategy on its own accord and give itself within this strategy the responsibility for storing information. Moreover, the cell is even unaware of such a need; much less does it feel the need to employ such a strategy.
In addition, there is another important question that needs to be answered about the strong memories of the memory cells. In a normal human being, eight million cells die every second to be replaced by new ones. Therefore, the metabolism continuously renews itself. Yet the life span of memory cells is much longer than the life span of other cells. This characteristic helps them to protect people from diseases thanks to the information in their memories. These cells, however, are not everlasting. Though a long time later, they eventually die. At this point, we are left with a very surprising situation. Memory cells transfer the information they possess to the next generation before they die. People are indebted to these memory cells for not having to be afflicted all over again by the same in diseases they caught in infancy (measles, mumps, etc.).
How then can this cell know that it has to transfer this information?
This surely cannot be attributed to the cell itself, but to the ability granted to it by its Creator.
They do not need to expend much effort to do this, because these cells and the antibodies they manufacture are able to recognize the enemy directly from their shapes without any assistance. A receptor on their surface meets the antigen for which it was programmed, and binds to several small parts on it. Thus, the antigen is identified as a foreigner. In this way, B cells can easily recognize antigens, such as bacteria.
As outlined in detail in the section on "Antibodies", the B cells use the genes in the human body to manufacture antibodies. However, the number of genes in the human body is less than the number of antibodies produced. This situation causes no problem for the cells. Despite all these limitations, they succeed in producing nearly 2 million antibody types an hour.9 B cells interact in various combinations with available genes to make the above-mentioned production. It is literally impossible for a cell to think up these combinations. These unconscious cells are given the ability to involve themselves in these combinations by the will of Allah. This is because "...When He decides on something, He just says to it, 'Be!' and it is." (Surat al-Baqara:117)
No other force in the heavens and on the earth save Allah is capable of ordering even a single feature of the trillions of cells. It becomes possible only by the will of Allah that a cell performs such mathematical operations as producing the most appropriate weapon to inactivate every enemy that has invaded the cell.
In the first test, it is checked whether the cell can recognize the enemy or not. The cells recognizes the enemy with the assistance of "MHC"(Major Histocompatibility Complex) located on the surface of the enemy, which is a molecule that subjects the antigen to a series of chemical processes and presents it to the T cells.
Eventually, only those cells that are able to identify the enemy can survive. The others are not tolerated and they are immediately destroyed.
The recognition of enemy cells alone does not ensure
the survival of T cells. These cells must also have a very good
knowledge of the harmless substances and the regular tissues of
the human body so to as prevent unnecessary conflict, which will
eventually harm the body.
There is very limited information on the signals that cause the cells to die a programmed death, to continue to live, or to mature and transform themselves. From a scientific point of view, this remains one of the unsolved mysteries of the defence system. Many similar cells in our body receive signals from somewhere, and start functioning upon this signal. How can these cells, which send signals to one another, be aware of the need to send a signal? Mahlon B. Hoagland brings up the same question in his book, The Roots of Life:
How do the cells know when to stop growing? What tells them that the organs of which they're a part are not just the right size?… What is the nature of the division stopping signal(s)? We don't know the answer and we continue to search for it. 10Indeed, the mystery of the signaling between cells has not been solved yet.
A stem cell would normally be expected to divide to form two new cells bearing the same features. However, a switch hidden in one of the cells is turned on causing a sudden transformation in the cell. This new cell is the T cell that will fight for the human body. This leads us to ask the following question:
Why does a cell transform itself into a totally different cell?
Science has not answered this question yet. Science can answer the question of how the cell transforms itself, but it can never explain why the cell would want to become a fighter cell. Nor can it explain who programmed the cell to become a cell that defends the body when the need arises.
Only those who acknowledge the being of Allah can fully comprehend the answers to these questions.
Helper T cells secrete a molecule called lymphokine to stimulate other cells. This molecule somehow turns on a switch in other cells and starts off the war alarm.
The ability of the helper T cell to produce a molecule,
which activates another cell, is a very important process.
First, the production of this molecule is related to an impending war strategy. It is obvious that the cells cannot make up this strategy themselves, nor can the strategy come about by sheer coincidence.
Developing a strategy would not be enough either. The molecule in the cell, which will switch on the production key in the other cell, should be synthesized accurately. For this, it has to be perfectly aware of the chemical structure of the opposite cell.
A mistake made in the production of this molecule alone would paralyze the defence system entirely. This is because an army without communication would be destroyed even before it launched its defence.
The existence of this molecule alone suffices to prove the absurdity of the theory of evolution. This is because the prerequisite of the system is the existence of this molecule right from the outset. If helper T cells failed to alert other cells with the help of this molecule, the human body would surrender to viruses.
A closer examination of how killer T cells kill sick cells would reveal a great wisdom and an artistry in creation.
The killer T cells first have to distinguish between normal cells and those in which invaders hide. They deal with this problem with the help of the innate system (MHC molecules) granted to them. When they locate the invaded cell, they secrete a chemical substance. This secretion sinks into the membrane of the cell forming a hole by lining up sideways in close formation. Following this, leaking starts in the cell which is full of pores, and the cell dies.
Killer T cells store this chemical weapon in granular form. This way, this chemical weapon is always kept ready for use. Scientists were amazed to discover the fact that the cell produces its own weapon by itself and stores it for future use. Even more amazing are the details in the mind-boggling way the cell uses this chemical weapon.
When an enemy approaches the host cell, these microgranules move to the tip of the cell in the direction of the enemy. Afterwards, they come in contact with the cell membrane, melt into it, and by extending towards the outside, they release the substance contained within them.
From time to time, invader cells take very sinister courses. They sometimes hide so well in body cells that neither antibodies nor T cells recognize the enemy. Everything seems usual from the outside. In such cases, the defence system somehow suspects an anomaly and "NK" cells rush to that region through the blood. Killer lymphocytes surround the cell and start to push the cell around. At that stage, the enemy cell is killed by a toxigenic substance injected inside it.
How these cells identify the enemy is yet another unanswered question about the defence system. The receptors that should be present on their surfaces to enable them to identify of the target cells have not yet been discovered. Therefore, the mechanism they employ in identifying the enemy has not yet been clearly understood.
Despite all the technology at its disposal, mankind has still not been able to solve the details of the system these cells use to identify the enemy. Perhaps future technological advances will throw light on this system and this subject will no longer be a mystery. This, too, would be a piece of evidence proving the perfection of the current system, and what an intricate plan is involved in its creation.
- Eosinophil: These blood cells have the ability to perform phagocytosis, i.e. destroy (phagocytose) any foreign cells entering the body.
- Basophil: A big, rough and single-nucleus blood cell which is found in small quantities in the blood, and abundantly in the dermal, splenic and intestinal connective tissues.
- Neutrophils: With an antibacterial quality, these blood cells protect the organism against foreign materials. In addition, they help the defence system with their phagocytosis capabilities.
Antigen Presenting Cells: "APC"
The duty of these cells is to present the antigen (enemy) to the T cells. Why a cell would serve such a function - an important responsibility - definitely needs further consideration. It knows that the T cells defend the human body, identify the enemy and present the enemy it captures to the T cells for them to provide intelligence about it.
Why would the cell do this? According to the theory
of evolution, this cell should be concerned only about its own well-being.
However, it serves the system, although it receives no benefit from
What is even more interesting is that the APC are very well aware of the requirements of the T cells. Based on this, the APC will break down the enemy cell and present to the T cell only the amino acid sequence. This means that the APC is even aware that the T cell will extract the required information from this sequence.
At this point, it would be useful to recall one thing: We mentioned actions such as "knowing", "calculating", "thinking", "serving". Unquestionably, those actions require a certain consciousness. It is virtually impossible for a being with no consciousness or will to perform these actions. Yet, here we are talking about these abilities as being inherent in these minuscule entities: common, tiny, unconscious cells. Therefore, who gives this consciousness, ability, and a glorious system to these cells?
The answer to this question is very evident. It is Allah Who creates the APC and the T cell, as well as all other cells in the body, in a harmonious way to serve in the same system.
Allah is Known Through Reason
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